XLO - Xilio Therapeutics, Inc.
About Xilio Therapeutics, Inc. (https://www.xiliotx.com)
Xilio Therapeutics, Inc. is a clinical-stage biotechnology firm dedicated to crafting immunotherapies aimed at strengthening the immune systems of cancer patients. A key part of their pipeline is XTX101, a tumor-selective anti-CTLA-4 monoclonal antibody that is currently undergoing Phase 1/2 clinical trials for various solid tumors. The company also develops a range of cytokine programs, including XTX202 (a modified IL-2), XTX301 (an IL-12 product candidate), and XTX401 (an IL-15 product candidate). These cytokine therapies are ingeniously engineered with a protein domain that keeps them inactive until proteases specific to the tumor microenvironment (TME) cleave this mask, thereby initiating their therapeutic activity. Xilio Therapeutics, Inc. was founded in 2016 and is based in Waltham, Massachusetts.
Key Executives
| NAME | TITLE | DOB | SALARY |
|---|---|---|---|
| Rene Russo BCPS | President, Chief Executive Officer & Director | 1975 | $1,158,176 USD |
| Christopher Frankenfield | Chief Financial Officer & Chief Operating Officer | 1982 | $941,594 USD |
| Katarina Luptakova | Chief Medical Officer | 1976 | $691,670 USD |
| Caroline Hensley | Chief Legal Officer | – | – |
| Kevin Brennan | Senior Vice President of Finance & Accounting | 1970 | – |
| Nathan McBride | Chief Information Officer | – | – |
| Ruth du Moulin | Senior Vice President of Medical Affairs | – | – |
| Scott Coleman | Chief Development Officer | – | – |
| Uli Bialucha | Chief Scientific Officer | – | – |