UPB - Upstream Bio, Inc.
Price:
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--
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CONSENSUS:
Buy
DETAILS
|
PRICE TARGET:
$33.00
DETAILS
HIGH:
$51.00
LOW:
$15.00
MEDIAN:
$33.00
CONSENSUS:
$33.00
UPSIDE:
294.27%
| Metric | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Revenue | ||||
| Revenue | 2.9 | 2.4 | 2.4 | 1.2 |
| Cost of Revenue | 0 | 0 | 0 | 0 |
| Gross Profit | 2.9 | 2.4 | 2.4 | 1.2 |
| Operating Expenses | ||||
| R&D Expenses | 136.8 | 63.0 | 31.8 | 18.7 |
| SG&A Expenses | 26.4 | 17.2 | 10.7 | 6.5 |
| Other Expenses | 0 | 0 | 0 | 0 |
| Operating Expenses | 163.2 | 80.1 | 42.5 | 25.1 |
| Operating Income | ||||
| Operating Income | (160.4) | (77.8) | (40.1) | (23.9) |
| Interest Expense | 0 | 0 | 0 | 0 |
| Interest Income | 16.9 | 12.1 | 4.2 | 0.2 |
| Profitability | ||||
| EBITDA | (160.2) | (77.7) | (40.1) | (23.9) |
| EBIT | (160.4) | (77.8) | (40.1) | (23.9) |
| Income Before Tax | (143.4) | (62.8) | (20.5) | (23.9) |
| Income Tax Expense | 0 | 0 | 0 | 0 |
| Net Income | (143.4) | (62.8) | (20.5) | (23.9) |
| Per Share Data | ||||
| EPS (Basic) | -2.66 | -1.49 | -1.05 | -0.66 |
| EPS (Diluted) | -2.66 | -1.49 | -1.05 | -0.66 |
| Shares Outstanding | 53.9 | 51.3 | 36.3 | 36.3 |
| Metric | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Current Assets | ||||
| Cash & Cash Equivalents | 101.6 | 325.9 | 25.8 | 17.1 |
| Short-Term Investments | 239.9 | 144.6 | 84.0 | 0 |
| Net Receivables | 0.7 | 1.2 | 0.2 | 0.4 |
| Inventory | 0 | 0 | 0 | 0 |
| Other Current Assets | 9.6 | 0.5 | 0.4 | 0.2 |
| Total Current Assets | 351.8 | 479.2 | 117.0 | 18.3 |
| Non-Current Assets | ||||
| Property, Plant & Equipment | 1.8 | 2.4 | 0.2 | 0.2 |
| Goodwill | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 0 | 0 |
| Other Non-Current Assets | 0.2 | 0.2 | 0 | 0.0 |
| Total Non-Current Assets | 2.0 | 2.6 | 0.2 | 0.2 |
| Total Assets | 353.8 | 481.7 | 117.2 | 18.5 |
| Current Liabilities | ||||
| Account Payables | 2.7 | 4.0 | 2.0 | 0.7 |
| Short-Term Debt | 0.7 | 0 | 0 | 0 |
| Deferred Revenue | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 10.0 | 2.7 | 2.2 | 0.9 |
| Total Current Liabilities | 13.5 | 10.7 | 6.5 | 4.9 |
| Non-Current Liabilities | ||||
| Long-Term Debt | 0.5 | 0 | 0 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 0 | 233.8 | 119.8 |
| Total Non-Current Liabilities | 0.5 | 1.1 | 233.8 | 119.8 |
| Total Liabilities | 14.0 | 11.9 | 240.3 | 124.6 |
| Stockholders' Equity | ||||
| Common Stock | 0.1 | 0.1 | 0.0 | 0.0 |
| Retained Earnings | (334.2) | (190.8) | (128.0) | (107.4) |
| Accumulated Other Comprehensive Income | 0.5 | (0.0) | 0.0 | 0 |
| Total Stockholders' Equity | 339.8 | 469.9 | (123.1) | (106.2) |
| Total Liabilities & Equity | 353.8 | 481.7 | 117.2 | 18.5 |
| Debt Metrics | ||||
| Total Debt | 1.3 | 1.8 | 0.0 | 0.1 |
| Net Debt | (100.3) | (324.1) | (25.8) | (17.0) |
| Metric | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Operating Activities | ||||
| Net Income | (143.4) | (62.8) | (20.5) | (23.9) |
| Depreciation & Amortization | (1.3) | 0.1 | 0.1 | 0.0 |
| Stock-Based Compensation | 10.3 | 6.0 | 3.4 | 1.3 |
| Change in Working Capital | 0.6 | 1.9 | (4.3) | 3.4 |
| Other Non-Cash Items | 0.6 | (4.3) | (16.6) | 0.1 |
| Operating Cash Flow | (133.3) | (59.2) | (37.9) | (19.0) |
| Investing Activities | ||||
| Capital Expenditure | (0.2) | (0.5) | (0.1) | (0.1) |
| Acquisitions | 0 | 0 | 0 | 0 |
| Purchases of Investments | (385.9) | (290.6) | (129.0) | 0 |
| Sales/Maturities of Investments | 292.6 | 231.6 | 46.3 | 0 |
| Other Investing Activities | 0 | 0 | 0 | 0 |
| Investing Cash Flow | (93.5) | (59.5) | (82.8) | (0.1) |
| Financing Activities | ||||
| Net Debt Issuance | 0 | 0 | 0 | 0 |
| Stock Repurchased | 0 | 0 | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 |
| Other Financing Activities | 0 | (3.7) | 0.1 | (0.0) |
| Financing Cash Flow | 2.4 | 418.9 | 129.6 | 10.0 |
| Cash Position | ||||
| Net Change in Cash | (224.3) | 300.3 | 8.8 | (9.1) |
| Cash at Beginning | 326.1 | 25.8 | 17.1 | 26.2 |
| Cash at End | 101.8 | 326.1 | 25.8 | 17.1 |
| Free Cash Flow | (133.3) | (59.7) | (38.1) | (19.1) |
| Key Metrics | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Income Statement | ||||
| Revenue | 2.9 | 2.4 | 2.4 | 1.2 |
| Gross Profit | 2.9 | 2.4 | 2.4 | 1.2 |
| Operating Income | (160.4) | (77.8) | (40.1) | (23.9) |
| Net Income | (143.4) | (62.8) | (20.5) | (23.9) |
| EPS (Diluted) | -2.66 | -1.49 | -1.05 | -0.66 |
| Balance Sheet | ||||
| Cash & Equivalents | 101.6 | 325.9 | 25.8 | 17.1 |
| Total Assets | 353.8 | 481.7 | 117.2 | 18.5 |
| Total Debt | 1.3 | 1.8 | 0.0 | 0.1 |
| Stockholders' Equity | 339.8 | 469.9 | (123.1) | (106.2) |
| Cash Flow | ||||
| Operating Cash Flow | (133.3) | (59.2) | (37.9) | (19.0) |
| Capital Expenditure | (0.2) | (0.5) | (0.1) | (0.1) |
| Free Cash Flow | (133.3) | (59.7) | (38.1) | (19.1) |