DNLI - Denali Therapeutics Inc.
Price:
--
--
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CONSENSUS:
Buy
DETAILS
|
PRICE TARGET:
$30.80
DETAILS
HIGH:
$40.00
LOW:
$23.00
MEDIAN:
$31.00
CONSENSUS:
$30.80
UPSIDE:
65.24%
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | |||||||||||
| Revenue | 0 | 0 | 330.5 | 108.5 | 48.7 | 335.7 | 26.7 | 129.2 | 0 | 0 | 0 |
| Cost of Revenue | 11.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.1 | 1.5 | 0.1 |
| Gross Profit | (11.2) | 0 | 330.5 | 108.5 | 48.7 | 335.7 | 26.7 | 129.2 | (3.1) | (1.5) | (0.1) |
| Operating Expenses | |||||||||||
| R&D Expenses | 418.8 | 396.4 | 423.9 | 358.7 | 265.4 | 212.6 | 193.4 | 143.2 | 74.5 | 75.7 | 11.6 |
| SG&A Expenses | 97.1 | 105.4 | 103.4 | 90.5 | 79.1 | 60.3 | 46.5 | 32.3 | 15.7 | 11.7 | 5.1 |
| Other Expenses | 28.3 | (14.5) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Operating Expenses | 544.2 | 487.3 | 527.2 | 449.2 | 344.4 | 272.9 | 239.9 | 175.5 | 90.1 | 87.4 | 16.7 |
| Operating Income | |||||||||||
| Operating Income | (555.3) | (487.3) | (196.7) | (340.7) | (295.8) | 62.7 | (213.2) | (46.4) | (90.1) | (87.4) | (16.7) |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.0 | 0 | 0.1 |
| Interest Income | 42.9 | 64.6 | 51.5 | 14.8 | 4.6 | 9.2 | 15.2 | 10.1 | 2.0 | 0.8 | 0 |
| Profitability | |||||||||||
| EBITDA | (497.6) | (492.9) | (180.0) | (330.4) | (287.2) | 71.2 | (205.2) | (39.0) | (87.1) | (86.0) | (15.1) |
| EBIT | (512.4) | (501.9) | (196.7) | (340.7) | (295.8) | 62.7 | (213.2) | (46.4) | (90.1) | (87.4) | (16.7) |
| Income Before Tax | (512.4) | (422.7) | (145.2) | (326.0) | (291.2) | 72.0 | (198.0) | (36.2) | (88.2) | (86.7) | (16.8) |
| Income Tax Expense | 0.1 | 0.1 | 0.0 | 0.0 | (0.6) | 0.8 | (0.4) | 0 | 0 | 0 | 0 |
| Net Income | (512.5) | (422.8) | (145.2) | (326.0) | (290.6) | 71.1 | (197.6) | (36.2) | (88.2) | (86.7) | (16.8) |
| Per Share Data | |||||||||||
| EPS (Basic) | -2.97 | -2.57 | -1.06 | -2.60 | -2.39 | 0.65 | -2.07 | -0.39 | -5.89 | -13.49 | -5.58 |
| EPS (Diluted) | -2.97 | -2.57 | -1.06 | -2.60 | -2.39 | 0.63 | -2.07 | -0.39 | -5.89 | -13.49 | -5.58 |
| Shares Outstanding | 175.5 | 164.5 | 137.4 | 125.5 | 121.5 | 109.0 | 95.6 | 92.6 | 15.0 | 6.4 | 3.0 |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Assets | ||||||||||
| Cash & Cash Equivalents | 205.3 | 175.0 | 127.1 | 218.0 | 293.5 | 507.1 | 79.4 | 77.1 | 218.4 | 39.9 |
| Short-Term Investments | 662.6 | 657.4 | 907.4 | 1,118.2 | 571.9 | 962.6 | 335.9 | 387.2 | 187.9 | 138.5 |
| Net Receivables | 2.2 | 2.2 | 3.4 | 9.3 | 1.2 | 0 | 0 | 8.5 | 0.5 | 0.4 |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | (8.5) | (0.5) | 0 |
| Other Current Assets | 30.6 | 0 | 0 | 0 | 0 | 26.0 | 0 | 1.4 | 0 | 0 |
| Total Current Assets | 900.7 | 864.4 | 1,064.1 | 1,372.3 | 897.2 | 1,495.7 | 430.0 | 480.8 | 409.6 | 182.0 |
| Non-Current Assets | ||||||||||
| Property, Plant & Equipment | 119.9 | 125.6 | 71.6 | 74.5 | 69.6 | 73.5 | 80.7 | 25.2 | 14.9 | 15.3 |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 359.4 | 0 | 0 | 425.4 | 34.2 | 39.9 | 147.9 | 60.8 | 73.1 |
| Other Non-Current Assets | 124.3 | 24.7 | 18.1 | 13.4 | 11.9 | 1.0 | 2.7 | 8.1 | 1.4 | 0.8 |
| Total Non-Current Assets | 244.2 | 509.7 | 89.8 | 87.9 | 506.9 | 108.6 | 123.2 | 181.1 | 77.1 | 89.1 |
| Total Assets | 1,144.9 | 1,374.2 | 1,153.9 | 1,460.2 | 1,404.2 | 1,604.3 | 553.2 | 662.0 | 486.7 | 271.1 |
| Current Liabilities | ||||||||||
| Account Payables | 3.3 | 11.1 | 9.5 | 2.8 | 4.8 | 1.1 | 2.6 | 1.9 | 2.7 | 2.0 |
| Short-Term Debt | 9.5 | 0 | 0 | 0 | 0 | 4.7 | 0 | 0 | 0 | 0 |
| Deferred Revenue | 0 | 0 | 0 | 290.1 | 320.3 | 23.5 | 18.7 | 11.4 | 0 | 0 |
| Other Current Liabilities | 85.5 | 38.9 | 21.6 | 17.1 | 19.0 | 22.0 | 8.7 | 9.5 | 0.9 | 0.7 |
| Total Current Liabilities | 98.4 | 102.2 | 78.0 | 363.9 | 378.2 | 71.7 | 45.3 | 32.8 | 14.2 | 9.1 |
| Non-Current Liabilities | ||||||||||
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 5.6 | 0 | 0.4 | 0.4 | 0.7 | 0.4 | 25.0 | 6.8 | 7.4 |
| Total Non-Current Liabilities | 32.7 | 42.3 | 45.0 | 53.9 | 63.6 | 382.1 | 113.0 | 82.4 | 6.8 | 7.4 |
| Total Liabilities | 131.1 | 144.5 | 123.0 | 417.8 | 441.9 | 453.7 | 158.3 | 115.1 | 20.9 | 16.5 |
| Stockholders' Equity | ||||||||||
| Common Stock | 1.9 | 1.8 | 1.7 | 1.7 | 1.5 | 1.5 | 1.3 | 1.3 | 1.2 | 2.7 |
| Retained Earnings | (2,051.5) | (1,539.0) | (1,116.2) | (971.0) | (645.0) | (354.4) | (425.6) | (227.9) | (191.7) | (103.5) |
| Accumulated Other Comprehensive Income | 0.7 | 2.0 | 0.6 | (6.9) | (2.5) | (0.2) | 0.3 | (0.6) | (0.4) | (0.4) |
| Total Stockholders' Equity | 1,013.8 | 1,229.7 | 1,031.0 | 1,042.4 | 962.3 | 1,150.5 | 394.9 | 546.8 | 465.8 | 254.5 |
| Total Liabilities & Equity | 1,144.9 | 1,374.2 | 1,153.9 | 1,460.2 | 1,404.2 | 1,604.3 | 553.2 | 662.0 | 486.7 | 271.1 |
| Debt Metrics | ||||||||||
| Total Debt | 42.3 | 48.7 | 52.2 | 60.4 | 64.0 | 68.9 | 72.5 | 0 | 0 | 0 |
| Net Debt | (163.0) | (126.3) | (74.9) | (157.7) | (229.5) | (438.3) | (6.9) | (77.1) | (218.4) | (39.9) |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Activities | ||||||||||
| Net Income | (512.5) | (422.8) | (145.2) | (326.0) | (290.6) | 71.1 | (197.6) | (36.2) | (88.2) | (86.7) |
| Depreciation & Amortization | 14.8 | 9.0 | 16.7 | 10.4 | 8.6 | 8.5 | 8.0 | 7.4 | 3.1 | 1.5 |
| Stock-Based Compensation | 99.6 | 102.9 | 108.1 | 99.8 | 85.2 | 50.4 | 38.4 | 18.8 | 4.4 | 3.0 |
| Change in Working Capital | 0.1 | 16.9 | (289.9) | (24.0) | (20.4) | 288.4 | 2.9 | 62.9 | 3.3 | 4.3 |
| Other Non-Cash Items | (14.7) | (53.7) | (47.7) | (4.9) | 5.8 | (2.3) | (3.3) | (2.7) | 0.8 | 5.3 |
| Operating Cash Flow | (412.6) | (347.7) | (358.0) | (244.7) | (211.4) | 416.2 | (151.6) | 50.1 | (76.6) | (72.4) |
| Investing Activities | ||||||||||
| Capital Expenditure | (9.5) | (15.9) | (12.9) | (17.8) | (8.5) | (3.1) | (17.9) | (3.4) | (2.9) | (6.1) |
| Acquisitions | 0 | 0 | 0 | 123.6 | 0 | 620.1 | 0 | 0 | 0 | 0 |
| Purchases of Investments | (441.3) | (1,230.0) | (1,813.7) | (1,115.0) | (1,422.9) | (1,285.5) | (369.7) | (557.9) | (179.8) | (226.9) |
| Sales/Maturities of Investments | 706.0 | 1,157.1 | 2,075.9 | 991.5 | 1,409.8 | 665.4 | 535.3 | 273.9 | 141.5 | 14 |
| Other Investing Activities | 0 | 0 | 0 | (123.6) | 0 | (620.1) | 0 | (284.0) | (38.3) | (212.9) |
| Investing Cash Flow | 255.3 | (88.8) | 249.3 | (141.4) | (21.6) | (623.2) | 147.7 | (287.4) | (41.2) | (219.0) |
| Financing Activities | ||||||||||
| Net Debt Issuance | (8.2) | (32.3) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Stock Repurchased | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing Activities | 0 | 17.4 | 0 | 14.5 | 19.3 | 20.7 | 6.2 | 2.6 | 0.7 | 0.1 |
| Financing Cash Flow | 189.2 | 484.3 | 17.8 | 310.7 | 19.3 | 634.7 | 6.2 | 97.0 | 296.3 | 300.5 |
| Cash Position | ||||||||||
| Net Change in Cash | 31.9 | 47.9 | (90.9) | (75.4) | (213.7) | 427.7 | 2.3 | (140.3) | 178.5 | 9.1 |
| Cash at Beginning | 176.5 | 128.7 | 218.0 | 295.0 | 508.6 | 80.9 | 78.6 | 218.9 | 39.9 | 30.7 |
| Cash at End | 208.4 | 176.5 | 127.1 | 219.5 | 295.0 | 508.6 | 80.9 | 78.6 | 218.4 | 39.9 |
| Free Cash Flow | (422.1) | (363.6) | (370.9) | (262.5) | (219.9) | 413.1 | (169.5) | 46.7 | (79.5) | (78.5) |
| Key Metrics | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Income Statement | |||||||||||
| Revenue | 0 | 0 | 330.5 | 108.5 | 48.7 | 335.7 | 26.7 | 129.2 | 0 | 0 | 0 |
| Gross Profit | (11.2) | 0 | 330.5 | 108.5 | 48.7 | 335.7 | 26.7 | 129.2 | (3.1) | (1.5) | (0.1) |
| Operating Income | (555.3) | (487.3) | (196.7) | (340.7) | (295.8) | 62.7 | (213.2) | (46.4) | (90.1) | (87.4) | (16.7) |
| Net Income | (512.5) | (422.8) | (145.2) | (326.0) | (290.6) | 71.1 | (197.6) | (36.2) | (88.2) | (86.7) | (16.8) |
| EPS (Diluted) | -2.97 | -2.57 | -1.06 | -2.60 | -2.39 | 0.63 | -2.07 | -0.39 | -5.89 | -13.49 | -5.58 |
| Balance Sheet | |||||||||||
| Cash & Equivalents | 205.3 | 175.0 | 127.1 | 218.0 | 293.5 | 507.1 | 79.4 | 77.1 | 218.4 | 39.9 | |
| Total Assets | 1,144.9 | 1,374.2 | 1,153.9 | 1,460.2 | 1,404.2 | 1,604.3 | 553.2 | 662.0 | 486.7 | 271.1 | |
| Total Debt | 42.3 | 48.7 | 52.2 | 60.4 | 64.0 | 68.9 | 72.5 | 0 | 0 | 0 | |
| Stockholders' Equity | 1,013.8 | 1,229.7 | 1,031.0 | 1,042.4 | 962.3 | 1,150.5 | 394.9 | 546.8 | 465.8 | 254.5 | |
| Cash Flow | |||||||||||
| Operating Cash Flow | (412.6) | (347.7) | (358.0) | (244.7) | (211.4) | 416.2 | (151.6) | 50.1 | (76.6) | (72.4) | |
| Capital Expenditure | (9.5) | (15.9) | (12.9) | (17.8) | (8.5) | (3.1) | (17.9) | (3.4) | (2.9) | (6.1) | |
| Free Cash Flow | (422.1) | (363.6) | (370.9) | (262.5) | (219.9) | 413.1 | (169.5) | 46.7 | (79.5) | (78.5) | |