ALNY - Alnylam Pharmaceuticals, Inc.
Price:
--
--
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CONSENSUS:
Buy
DETAILS
|
PRICE TARGET:
$445.67
DETAILS
HIGH:
$530.00
LOW:
$351.00
MEDIAN:
$445.50
CONSENSUS:
$445.67
UPSIDE:
49.83%
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | ||||||||||||||||||||||||
| Revenue | 3,713.9 | 2,248.2 | 1,828.3 | 1,037.4 | 844.3 | 492.9 | 219.8 | 74.9 | 89.9 | 47.2 | 41.1 | 50.6 | 47.2 | 66.7 | 82.8 | 100.0 | 100.5 | 96.2 | 50.9 | 26.9 | 5.7 | 4.3 | 0.2 | 0 |
| Cost of Revenue | 677.2 | 323.4 | 310.4 | 168.8 | 140.1 | 78.1 | 25.1 | 1.8 | 13.4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Gross Profit | 3,036.8 | 1,924.9 | 1,517.9 | 868.6 | 704.1 | 414.8 | 194.7 | 73.1 | 76.5 | 47.2 | 41.1 | 50.6 | 47.2 | 66.7 | 82.8 | 100.0 | 100.5 | 96.2 | 50.9 | 26.9 | 5.7 | 4.3 | 0.2 | 0 |
| Operating Expenses | ||||||||||||||||||||||||
| R&D Expenses | 1,324.5 | 1,126.2 | 1,004.4 | 883.0 | 792.2 | 654.8 | 655.1 | 505.4 | 390.6 | 382.4 | 276.5 | 190.2 | 113.0 | 86.6 | 99.3 | 106.4 | 108.7 | 96.9 | 120.7 | 49.8 | 35.3 | 24.6 | 13.1 | 3.3 |
| SG&A Expenses | 1,210.7 | 975.5 | 795.6 | 770.7 | 620.6 | 588.4 | 479.0 | 382.4 | 199.4 | 89.4 | 60.6 | 44.5 | 27.2 | 44.6 | 38.3 | 37.7 | 39.9 | 27.1 | 23.4 | 16.6 | 13.9 | 11.9 | 7.5 | 0.9 |
| Other Expenses | 0 | 0 | 0 | 0 | (2.0) | 0 | 0 | 4.2 | (3.0) | 0 | 0.1 | 1.8 | (0.0) | 0.3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Operating Expenses | 2,535.2 | 2,101.8 | 1,800.1 | 1,653.7 | 1,412.8 | 1,243.2 | 1,134.1 | 887.8 | 590 | 471.7 | 337.1 | 234.8 | 140.1 | 131.2 | 137.6 | 144.1 | 148.6 | 124.0 | 144.1 | 66.4 | 49.2 | 36.5 | 20.6 | 4.2 |
| Operating Income | ||||||||||||||||||||||||
| Operating Income | 501.6 | (176.9) | (282.2) | (785.1) | (708.7) | (828.4) | (939.4) | (814.7) | (500.1) | (424.6) | (296.0) | (405.0) | (92.9) | (129.5) | (54.8) | (44.1) | (48.1) | (27.8) | (93.2) | (39.5) | (43.5) | (32.3) | (25.1) | (4.2) |
| Interest Expense | 252.6 | 141.9 | 121.2 | 156.0 | 143.0 | 84.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.9 | 1.1 | 0 | 0 | 0 | 0 | 0 |
| Interest Income | 111.5 | 122.0 | 95.6 | 24.8 | 1.6 | 11.8 | 33.4 | 29.3 | 12.2 | 8.3 | 5.9 | 2.6 | 1.1 | 1.0 | 1.2 | 2.3 | 5.4 | 14.4 | 15.4 | 0 | 0 | 0 | 0 | 0 |
| Profitability | ||||||||||||||||||||||||
| EBITDA | 557.2 | (178.8) | (258.2) | (926.6) | (661.6) | (736.3) | (868.1) | (754.2) | (488.2) | (409.5) | (277.0) | (172.3) | (82.7) | (51.7) | (49.7) | (38.1) | (41.0) | (18.9) | (75.1) | (35.7) | (38.8) | (29.5) | (19.6) | (4.2) |
| EBIT | 501.6 | (235.5) | (312.3) | (971.0) | (709.1) | (771.1) | (885.3) | (760.7) | (500.1) | (424.6) | (296.0) | (184.2) | (92.9) | (63.6) | (57.6) | (43.7) | (47.0) | (24.7) | (79.1) | (39.5) | (43.5) | (32.3) | (20.4) | (4.2) |
| Income Before Tax | 323.2 | (377.4) | (433.5) | (1,127.0) | (852.1) | (855.6) | (885.3) | (760.7) | (490.9) | (410.1) | (290.1) | (400.6) | (91.9) | (116.6) | (57.6) | (43.0) | (47.0) | (25.5) | (80.2) | (34.6) | (42.9) | (35.4) | (29.7) | 0 |
| Income Tax Expense | 9.4 | (99.2) | 6.7 | 4.2 | 0.7 | 2.7 | 0.9 | 0.8 | 0 | 0 | 0 | (40.2) | (2.7) | (10.6) | 0 | 0.5 | 0.6 | 0.7 | 5.2 | 0 | 0 | 0.4 | (4.6) | (0.1) |
| Net Income | 313.7 | (278.2) | (440.2) | (1,131.2) | (852.8) | (858.3) | (886.1) | (761.5) | (490.9) | (410.1) | (290.1) | (360.4) | (89.2) | (106.0) | (57.6) | (43.5) | (47.6) | (26.2) | (85.5) | (34.6) | (42.9) | (32.7) | (25.0) | (4.1) |
| Per Share Data | ||||||||||||||||||||||||
| EPS (Basic) | 2.39 | -2.18 | -3.52 | -9.30 | -7.20 | -7.46 | -8.11 | -7.57 | -5.42 | -4.79 | -3.45 | -4.85 | -1.45 | -2.11 | -1.36 | -1.04 | -1.14 | -0.64 | -2.21 | -1.09 | -1.96 | -2.75 | -26.56 | -12.48 |
| EPS (Diluted) | 2.33 | -2.18 | -3.52 | -9.30 | -7.20 | -7.46 | -8.11 | -7.57 | -5.42 | -4.79 | -3.45 | -4.85 | -1.45 | -2.11 | -1.36 | -1.04 | -1.14 | -0.64 | -2.21 | -1.09 | -1.96 | -2.75 | -26.56 | -12.48 |
| Shares Outstanding | 131.0 | 127.7 | 124.9 | 121.7 | 118.5 | 115.0 | 109.3 | 100.6 | 90.6 | 85.6 | 84.0 | 74.3 | 61.6 | 50.3 | 42.4 | 42.0 | 41.6 | 41.1 | 38.7 | 31.9 | 21.9 | 11.9 | 0.9 | 0.3 |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2009 | 2008 | 2004 | 2003 | 2002 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Assets | |||||||||||||||
| Cash & Cash Equivalents | 1,657.2 | 966.4 | 812.7 | 866.4 | 820.0 | 496.6 | 547.2 | 420.1 | 645.4 | 193.6 | 137.5 | 191.8 | 20.3 | 23.2 | 15.5 |
| Short-Term Investments | 1,251.2 | 1,728.1 | 1,626.7 | 1,326.0 | 1,615.6 | 1,377.8 | 989.0 | 664.0 | 1,045.3 | 433.2 | 143.9 | 238.6 | 25.8 | 0 | 0 |
| Net Receivables | 777.6 | 405.3 | 327.8 | 238.0 | 198.6 | 602.4 | 43.0 | 18.8 | 34.0 | 23.3 | 6.0 | 4.2 | 1.2 | 0 | 0 |
| Inventory | 82.7 | 78.5 | 89.1 | 129.0 | 86.4 | 75.2 | 56.3 | 24.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Assets | 281.9 | 117.0 | 126.4 | 132.9 | 0 | 0 | 0 | 0 | 0 | 0 | 1.9 | 3.9 | 0 | 0.4 | 0.0 |
| Total Current Assets | 4,050.7 | 3,295.3 | 2,982.7 | 2,692.2 | 2,808.6 | 2,614.8 | 1,715.9 | 1,200.7 | 1,764.7 | 671.9 | 293.5 | 443.1 | 48.2 | 24.2 | 15.5 |
| Non-Current Assets | |||||||||||||||
| Property, Plant & Equipment | 708.1 | 693.9 | 725.8 | 738.6 | 733.6 | 706.5 | 646.4 | 320.7 | 181.9 | 114.6 | 18.3 | 19.2 | 11.7 | 4.8 | 0.5 |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.6 | 0.8 | 3.4 | 3.9 | 0 |
| Long-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 14.8 | 44.8 | 13.9 | 324.8 | 160.3 | 83.9 | 0 | 0 | 0 |
| Other Non-Current Assets | 81.6 | 133.9 | 111.3 | 115.5 | 101.1 | 85.8 | 18.1 | 8.6 | 34.2 | 151.6 | 0 | 3.2 | 2.8 | 2.4 | 0.1 |
| Total Non-Current Assets | 915.7 | 944.7 | 847.2 | 854.1 | 834.7 | 792.3 | 679.3 | 374.1 | 230.0 | 590.9 | 187.9 | 111.6 | 17.9 | 11.0 | 0.6 |
| Total Assets | 4,966.3 | 4,240.0 | 3,829.9 | 3,546.4 | 3,643.3 | 3,407.1 | 2,395.1 | 1,574.8 | 1,994.7 | 1,262.8 | 481.4 | 554.7 | 66.1 | 35.2 | 16.1 |
| Current Liabilities | |||||||||||||||
| Account Payables | 115.7 | 88.4 | 55.5 | 98.1 | 73.4 | 52.0 | 49.9 | 59.7 | 28.4 | 54.5 | 12.5 | 2.6 | 0.9 | 1.5 | 0.7 |
| Short-Term Debt | 0 | 113.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.8 | 0.6 | 0 |
| Deferred Revenue | 4.8 | 55.5 | 102.8 | 42.1 | 149.5 | 127.2 | 77.8 | 3.5 | 41.7 | 33.5 | 82.8 | 79.9 | 1 | 0.3 | 0 |
| Other Current Liabilities | 477.3 | 214.4 | 177.2 | 171.0 | 130.7 | 110.7 | 68.3 | 40.9 | 35.8 | 15.3 | 0 | 1.6 | 0 | 0 | 0 |
| Total Current Liabilities | 1,466.3 | 1,186.3 | 967.8 | 767.9 | 695.7 | 585.3 | 352.6 | 179.5 | 144.3 | 131.7 | 110.7 | 99.5 | 6.6 | 3.8 | 2.7 |
| Non-Current Liabilities | |||||||||||||||
| Long-Term Debt | 1,007.8 | 2,359.0 | 1,020.8 | 1,016.9 | 675.7 | 191.3 | 0 | 30 | 30 | 150 | 0 | 0 | 6.4 | 1.3 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 1,477.9 | 398.1 | 1,630.7 | 1,464.6 | 1,250.0 | 1,096.1 | 9.3 | 62.9 | 11.0 | 11.5 | 2.8 | 3.0 | 7.0 | 56.7 | 18.1 |
| Total Non-Current Liabilities | 2,710.8 | 2,986.6 | 3,082.7 | 2,936.7 | 2,359.4 | 1,805.5 | 603.8 | 93.3 | 84.0 | 210.9 | 192.7 | 253.1 | 13.4 | 58.0 | 18.1 |
| Total Liabilities | 4,177.2 | 4,172.9 | 4,050.5 | 3,704.6 | 3,055.1 | 2,390.8 | 956.4 | 272.8 | 228.3 | 342.6 | 303.4 | 352.6 | 20.0 | 61.9 | 20.8 |
| Stockholders' Equity | |||||||||||||||
| Common Stock | 1.3 | 1.3 | 1.3 | 1.2 | 1.2 | 1.2 | 1.1 | 1.0 | 1.0 | 0.9 | 0.4 | 0.4 | 0.2 | 0 | 0 |
| Retained Earnings | (6,702.5) | (7,287.7) | (7,009.6) | (6,569.3) | (5,438.2) | (4,585.4) | (3,727.1) | (2,841.0) | (2,147.7) | (1,656.8) | (299.8) | (252.2) | (63.0) | (29.5) | (4.5) |
| Accumulated Other Comprehensive Income | (20.1) | (34.5) | (23.4) | (44.7) | (33.3) | (43.6) | (36.5) | (33.2) | (34.4) | (33.4) | 0.7 | 1.2 | (3.3) | (4.6) | (0.2) |
| Total Stockholders' Equity | 789.2 | 67.1 | (220.6) | (158.2) | 588.2 | 1,016.2 | 1,438.7 | 1,302.0 | 1,766.4 | 920.2 | 178.0 | 202.1 | 46.1 | (26.7) | (4.6) |
| Total Liabilities & Equity | 4,966.3 | 4,240.0 | 3,829.9 | 3,546.4 | 3,643.3 | 3,407.1 | 2,395.1 | 1,574.8 | 1,994.7 | 1,262.8 | 481.4 | 554.7 | 66.1 | 35.2 | 16.1 |
| Debt Metrics | |||||||||||||||
| Total Debt | 1,278.4 | 2,743.4 | 1,305.4 | 1,320.2 | 997.6 | 521.2 | 303.8 | 30 | 30 | 150 | 0 | 0 | 7.2 | 1.9 | 0 |
| Net Debt | (378.9) | 1,777.0 | 492.7 | 453.9 | 177.6 | 24.6 | (243.4) | (390.1) | (615.4) | (43.6) | (137.5) | (191.8) | (13.1) | (21.3) | (15.5) |
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2005 | 2004 | 2003 | 2002 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Activities | ||||||||||||||
| Net Income | 313.7 | (278.2) | (440.2) | (1,131.2) | (852.8) | (858.3) | (886.1) | (761.5) | (490.9) | (410.1) | (42.9) | (32.7) | (25.0) | (4.1) |
| Depreciation & Amortization | 55.7 | 56.7 | 97.0 | 85.5 | 89.7 | 74.4 | 54.4 | 6.4 | 13.4 | 15.1 | 3.1 | 2.4 | 0.8 | 0.0 |
| Stock-Based Compensation | 348.2 | 272.1 | 221.7 | 230.6 | 165.7 | 139.9 | 174.8 | 157.8 | 92.8 | 75.5 | 0 | 4.1 | 0 | 0 |
| Change in Working Capital | (444.8) | (214.1) | 10.8 | (35.6) | (162.8) | (12.7) | 402.4 | 45.1 | (2.9) | 17.2 | 16.8 | 3.5 | 2.9 | 2.6 |
| Other Non-Cash Items | 253.4 | 261.9 | 214.9 | 309.2 | 174.2 | 95.8 | (12.6) | (6.8) | 2.9 | 1.5 | 6.6 | 7.2 | 8.5 | 0.2 |
| Operating Cash Flow | 524.1 | (8.3) | 104.2 | (541.3) | (641.7) | (615.0) | (278.4) | (562.6) | (382.8) | (307.7) | (16.5) | (19.6) | (12.8) | (1.3) |
| Investing Activities | ||||||||||||||
| Capital Expenditure | (58.7) | (34.3) | (62.2) | (72.1) | (76.4) | (70.4) | (140.2) | (126.9) | (104.2) | (64.6) | (1.9) | (9.0) | (3.1) | (0.6) |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 40.4 | 0 | (0.1) | 0 |
| Purchases of Investments | (1,364.9) | (1,712.0) | (1,823.5) | (1,977.0) | (1,656.1) | (2,025.6) | (2,075.9) | (1,104.0) | (903.5) | (759.3) | (70.9) | (33.5) | 0 | 0 |
| Sales/Maturities of Investments | 1,802.3 | 1,571.7 | 1,553.8 | 2,231.6 | 1,463.5 | 1,691.7 | 1,775.4 | 1,518.7 | 597.3 | 1,116.5 | 32.4 | 7.7 | 0 | 0 |
| Other Investing Activities | 57.6 | 57.8 | (4.4) | (13.2) | (4.4) | (31.2) | 23 | (14.8) | 120 | (150) | (40.4) | 0 | 0 | 0 |
| Investing Cash Flow | 436.3 | (116.8) | (336.4) | 169.4 | (273.3) | (435.5) | (417.7) | 272.9 | (290.4) | 142.6 | (40.4) | (34.6) | (3.2) | (0.6) |
| Financing Activities | ||||||||||||||
| Net Debt Issuance | (546.9) | 0 | 0 | 254.0 | 500 | 200 | (30) | 0 | (120) | 150 | 0.2 | 5.3 | (1.1) | 0 |
| Stock Repurchased | 0 | 0 | 0 | 0 | 0 | 0 | 0 | (3.5) | (0.3) | (0.6) | 0 | 0 | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing Activities | (8.3) | (8.8) | 24.7 | (87.6) | 500.9 | 695.5 | 71.3 | 0 | 83.9 | 14.1 | 0 | 0.3 | (2.7) | (0.0) |
| Financing Cash Flow | (305.2) | 294.2 | 172.1 | 425.8 | 1,247.1 | 995.0 | 823.2 | 65.5 | 1,124.9 | 177.8 | 52.6 | 51.0 | 23.7 | 17.3 |
| Cash Position | ||||||||||||||
| Net Change in Cash | 690.2 | 153.8 | (53.7) | 46.4 | 323.1 | (50.6) | 127.0 | (224.2) | 451.7 | 12.7 | (4.5) | (2.9) | 7.7 | 17.3 |
| Cash at Beginning | 968.7 | 814.9 | 868.6 | 822.2 | 499.0 | 549.6 | 422.6 | 646.8 | 193.6 | 180.9 | 20.3 | 23.2 | 15.5 | (1.8) |
| Cash at End | 1,658.8 | 968.7 | 814.9 | 868.6 | 822.2 | 499.0 | 549.6 | 422.6 | 645.4 | 193.6 | 15.8 | 20.3 | 23.2 | 15.5 |
| Free Cash Flow | 465.4 | (42.6) | 41.9 | (613.3) | (718.1) | (685.3) | (418.6) | (689.5) | (487.0) | (372.3) | (18.4) | (28.6) | (15.9) | (1.8) |
| Key Metrics | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Income Statement | ||||||||||||||||||||||||
| Revenue | 3,713.9 | 2,248.2 | 1,828.3 | 1,037.4 | 844.3 | 492.9 | 219.8 | 74.9 | 89.9 | 47.2 | 41.1 | 50.6 | 47.2 | 66.7 | 82.8 | 100.0 | 100.5 | 96.2 | 50.9 | 26.9 | 5.7 | 4.3 | 0.2 | 0 |
| Gross Profit | 3,036.8 | 1,924.9 | 1,517.9 | 868.6 | 704.1 | 414.8 | 194.7 | 73.1 | 76.5 | 47.2 | 41.1 | 50.6 | 47.2 | 66.7 | 82.8 | 100.0 | 100.5 | 96.2 | 50.9 | 26.9 | 5.7 | 4.3 | 0.2 | 0 |
| Operating Income | 501.6 | (176.9) | (282.2) | (785.1) | (708.7) | (828.4) | (939.4) | (814.7) | (500.1) | (424.6) | (296.0) | (405.0) | (92.9) | (129.5) | (54.8) | (44.1) | (48.1) | (27.8) | (93.2) | (39.5) | (43.5) | (32.3) | (25.1) | (4.2) |
| Net Income | 313.7 | (278.2) | (440.2) | (1,131.2) | (852.8) | (858.3) | (886.1) | (761.5) | (490.9) | (410.1) | (290.1) | (360.4) | (89.2) | (106.0) | (57.6) | (43.5) | (47.6) | (26.2) | (85.5) | (34.6) | (42.9) | (32.7) | (25.0) | (4.1) |
| EPS (Diluted) | 2.33 | -2.18 | -3.52 | -9.30 | -7.20 | -7.46 | -8.11 | -7.57 | -5.42 | -4.79 | -3.45 | -4.85 | -1.45 | -2.11 | -1.36 | -1.04 | -1.14 | -0.64 | -2.21 | -1.09 | -1.96 | -2.75 | -26.56 | -12.48 |
| Balance Sheet | ||||||||||||||||||||||||
| Cash & Equivalents | 1,657.2 | 966.4 | 812.7 | 866.4 | 820.0 | 496.6 | 547.2 | 420.1 | 645.4 | 193.6 | 137.5 | 191.8 | 20.3 | 23.2 | 15.5 | |||||||||
| Total Assets | 4,966.3 | 4,240.0 | 3,829.9 | 3,546.4 | 3,643.3 | 3,407.1 | 2,395.1 | 1,574.8 | 1,994.7 | 1,262.8 | 481.4 | 554.7 | 66.1 | 35.2 | 16.1 | |||||||||
| Total Debt | 1,278.4 | 2,743.4 | 1,305.4 | 1,320.2 | 997.6 | 521.2 | 303.8 | 30 | 30 | 150 | 0 | 0 | 7.2 | 1.9 | 0 | |||||||||
| Stockholders' Equity | 789.2 | 67.1 | (220.6) | (158.2) | 588.2 | 1,016.2 | 1,438.7 | 1,302.0 | 1,766.4 | 920.2 | 178.0 | 202.1 | 46.1 | (26.7) | (4.6) | |||||||||
| Cash Flow | ||||||||||||||||||||||||
| Operating Cash Flow | 524.1 | (8.3) | 104.2 | (541.3) | (641.7) | (615.0) | (278.4) | (562.6) | (382.8) | (307.7) | (16.5) | (19.6) | (12.8) | (1.3) | ||||||||||
| Capital Expenditure | (58.7) | (34.3) | (62.2) | (72.1) | (76.4) | (70.4) | (140.2) | (126.9) | (104.2) | (64.6) | (1.9) | (9.0) | (3.1) | (0.6) | ||||||||||
| Free Cash Flow | 465.4 | (42.6) | 41.9 | (613.3) | (718.1) | (685.3) | (418.6) | (689.5) | (487.0) | (372.3) | (18.4) | (28.6) | (15.9) | (1.8) | ||||||||||