TWST Twist Bioscience Corporation
Stable Earnings Power
F 30.0 / 100 pillar composite

AlphaQuality composite grade, weighted for stable earnings power businesses.

⚠ 5 of the last 5 fiscal years showed negative net income — AlphaQuality will not grade above F for persistent unprofitability in a stable earnings power business.

Grade overrides the 30.0 pillar composite — hard gates always win.

Profitability

Weight: 20%
D- 30
  • 5yr Avg ROIC -20.2%
  • Operating Margin Trend +20.32 pp/yr

Capital Efficiency

Weight: 15%
F 0
  • 5yr Avg ROE -29.4%
  • 5yr Share-Count CAGR 8.8%

Growth Quality

Weight: 15%
A+ 100
  • 5yr Revenue CAGR 33.1%
  • Revenue-Growth Years (5) 5/5

Cash Generation

Weight: 15%
F 0
  • 5yr FCF Margin -65.6%
  • 5yr FCF/NI Conversion 0.00x

Balance Sheet

Weight: 20%
C 55
  • Net Debt / EBITDA 10.00x
  • Interest Coverage (EBIT/Int) 30.00x
  • Altman Z-Score 29.04

Stability

Weight: 15%
B 70
  • Negative-Revenue Years (5) 0/5
  • Piotroski F-Score 4

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Dumping

3 of 3 gurus held; 2 new buys; 1 added; 2 full exits.

Holders
3
Avg Δ position
+2441.8%
New buys
2
Full exits
2
As of Q2 2026