VRTX Vertex Pharmaceuticals Incorporated
Platform & Compounding FCF
B+ 79.9 / 100 composite

AlphaQuality composite grade, weighted for platform & compounding fcf businesses.

Profitability

Weight: 25%
C+ 60
  • 5yr Avg ROIC 17.1%
  • Operating Margin Trend -4.50 pp/yr

Capital Efficiency

Weight: 15%
A- 80
  • 5yr Avg ROE 17.1%
  • 5yr Share-Count CAGR -0.4%

Growth Quality

Weight: 25%
A- 85
  • 5yr Revenue CAGR 14.2%
  • 5yr EPS CAGR 8.3%
  • Revenue-Growth Years (5) 5/5

Cash Generation

Weight: 20%
A+ 97
  • 5yr FCF Margin 25.7%
  • 5yr FCF/NI Conversion 0.98x

Balance Sheet

Weight: 10%
A+ 99
  • Net Debt / EBITDA -0.56x
  • Interest Coverage (EBIT/Int) 350.11x
  • Altman Z-Score 12.73

Stability

Weight: 5%
C 51
  • EPS Volatility (σ/μ) 0.52
  • Negative-Revenue Years (5) 0/5
  • Piotroski F-Score 4

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Trimming

4 of 4 gurus held; 4 trimmed.

Holders
4
Avg Δ position
-45.5%
New buys
0
Full exits
0
As of Q2 2026