SNDX Syndax Pharmaceuticals, Inc.
High-Growth Software
F 27.6 / 100 pillar composite

AlphaQuality composite grade, weighted for high-growth software businesses.

⚠ 4 of the last 5 fiscal years showed negative net income — AlphaQuality will not grade above F for persistent unprofitability in a high-growth software business.

Grade overrides the 27.6 pillar composite — hard gates always win.

Profitability

Weight: 15%
F 0
  • 5yr Avg ROIC -34.4%
  • Operating Margin Trend -88.61 pp/yr

Capital Efficiency

Weight: 15%
F 0
  • 5yr Avg ROE -290.3%
  • 5yr Share-Count CAGR 13.6%

Growth Quality

Weight: 35%
D+ 43
  • 5yr Revenue CAGR 5.4%
  • 5yr EPS CAGR 0.0%
  • Revenue-Growth Years (5) 2/5

Cash Generation

Weight: 20%
D+ 44
  • 5yr FCF Margin -442.6%
  • 5yr FCF/NI Conversion 1.16x

Balance Sheet

Weight: 10%
F 0
  • Net Debt / EBITDA 10.00x
  • Interest Coverage (EBIT/Int) -7.45x
  • Altman Z-Score -1.85

Stability

Weight: 5%
B+ 77
  • EPS Volatility (σ/μ) 0.00
  • Piotroski F-Score 2
  • Negative-Revenue Years (5) 0/5

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Holding

2 of 2 gurus held; 1 added; 1 trimmed; 1 full exit.

Holders
2
Avg Δ position
-14.0%
New buys
0
Full exits
1
As of Q1 2026