PRME Prime Medicine, Inc.
Stable Earnings Power
F 18.0 / 100 pillar composite

AlphaQuality composite grade, weighted for stable earnings power businesses.

⚠ 5 of the last 5 fiscal years showed negative net income — AlphaQuality will not grade above F for persistent unprofitability in a stable earnings power business.

Grade overrides the 18.0 pillar composite — hard gates always win.

Profitability

Weight: 20%
F 0
  • 5yr Avg ROIC -66.1%

Capital Efficiency

Weight: 15%
F 0
  • 5yr Avg ROE -110.2%
  • 5yr Share-Count CAGR 9.2%

Growth Quality

Weight: 15%
F 17
  • 5yr Revenue CAGR -2.3%
  • Revenue-Growth Years (5) 1/5

Cash Generation

Weight: 15%
F 0
  • 5yr FCF Margin -3985.4%
  • 5yr FCF/NI Conversion 0.00x

Balance Sheet

Weight: 20%
D- 30
  • Net Debt / EBITDA 10.00x
  • Interest Coverage (EBIT/Int) 30.00x
  • Altman Z-Score -3.27

Stability

Weight: 15%
B- 64
  • Negative-Revenue Years (5) 0/5
  • Piotroski F-Score 3

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Dumping

2 of 2 gurus held; 1 added; 1 trimmed.

Holders
2 +1
Avg Δ position
-53.4%
New buys
0
Full exits
0
As of Q2 2026