DNLI Denali Therapeutics Inc.
Stable Earnings Power
F 30.0 / 100 pillar composite

AlphaQuality composite grade, weighted for stable earnings power businesses.

⚠ 5 of the last 5 fiscal years showed negative net income — AlphaQuality will not grade above F for persistent unprofitability in a stable earnings power business.

Grade overrides the 30.0 pillar composite — hard gates always win.

Profitability

Weight: 20%
D- 30
  • 5yr Avg ROIC -25.2%
  • Operating Margin Trend +274.13 pp/yr

Capital Efficiency

Weight: 15%
F 0
  • 5yr Avg ROE -32.1%
  • 5yr Share-Count CAGR 9.3%

Growth Quality

Weight: 15%
D+ 40
  • Revenue-Growth Years (5) 2/5

Cash Generation

Weight: 15%
F 0
  • 5yr FCF Margin -268.7%
  • 5yr FCF/NI Conversion 0.00x

Balance Sheet

Weight: 20%
C 55
  • Net Debt / EBITDA 10.00x
  • Interest Coverage (EBIT/Int) 30.00x
  • Altman Z-Score 9.74

Stability

Weight: 15%
C- 48
  • Negative-Revenue Years (5) 1/5
  • Piotroski F-Score 2

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Holding

1 of 1 gurus held; 1 added.

Holders
1
Avg Δ position
+2.7%
New buys
0
Full exits
0
  • Wood increased +3%
As of Q2 2026