ALNY Alnylam Pharmaceuticals, Inc.
High-Growth Software
F 30.0 / 100 pillar composite

AlphaQuality composite grade, weighted for high-growth software businesses.

⚠ 4 of the last 5 fiscal years showed negative net income — AlphaQuality will not grade above F for persistent unprofitability in a high-growth software business.

Grade overrides the 30.0 pillar composite — hard gates always win.

Profitability

Weight: 15%
D- 30
  • 5yr Avg ROIC -16.2%
  • Operating Margin Trend +26.27 pp/yr

Capital Efficiency

Weight: 15%
F 6
  • 5yr Avg ROE -60.5%
  • 5yr Share-Count CAGR 3.3%

Growth Quality

Weight: 35%
B 72
  • 5yr Revenue CAGR 44.8%
  • 5yr EPS CAGR 0.0%
  • Revenue-Growth Years (5) 5/5

Cash Generation

Weight: 20%
D+ 41
  • 5yr FCF Margin -26.2%
  • 5yr FCF/NI Conversion 1.48x

Balance Sheet

Weight: 10%
B+ 78
  • Net Debt / EBITDA -2.93x
  • Interest Coverage (EBIT/Int) 1.99x
  • Altman Z-Score 5.98

Stability

Weight: 5%
A+ 93
  • EPS Volatility (σ/μ) 0.00
  • Piotroski F-Score 7
  • Negative-Revenue Years (5) 0/5

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Accumulating

4 of 4 gurus held; 3 added; 1 trimmed; 1 full exit.

Holders
4
Avg Δ position
+52.7%
New buys
0
Full exits
1
As of Q1 2026