AGIO Agios Pharmaceuticals, Inc.
Stable Earnings Power
F 30.0 / 100 pillar composite

AlphaQuality composite grade, weighted for stable earnings power businesses.

⚠ 3 of the last 5 fiscal years showed negative net income — AlphaQuality will not grade above F for persistent unprofitability in a stable earnings power business.

Grade overrides the 30.0 pillar composite — hard gates always win.

Profitability

Weight: 20%
D- 30
  • 5yr Avg ROIC -11.6%
  • Operating Margin Trend +586.77 pp/yr

Capital Efficiency

Weight: 15%
A- 83
  • 5yr Avg ROE 13.8%
  • 5yr Share-Count CAGR -3.4%

Growth Quality

Weight: 15%
C+ 60
  • Revenue-Growth Years (5) 3/5

Cash Generation

Weight: 15%
F 0
  • 5yr FCF Margin -1271.5%
  • 5yr FCF/NI Conversion -0.42x

Balance Sheet

Weight: 20%
C 55
  • Net Debt / EBITDA 10.00x
  • Interest Coverage (EBIT/Int) 30.00x
  • Altman Z-Score 10.12

Stability

Weight: 15%
C+ 58
  • Negative-Revenue Years (5) 0/5
  • Piotroski F-Score 2

Guru Flow

Curated superinvestor sentiment — not part of the AlphaQuality grade.
Accumulating

2 of 2 gurus held; 2 added.

Holders
2
Avg Δ position
+1680.2%
New buys
0
Full exits
0
As of Q2 2026